Christian McCaffrey ran for 145 yards on 16 carries in the 49ers 28-16 win over Seattle. He also caught his lone target for an additional eight yards through the air.
Fantasy Impact: On the very first play of the game, McCaffrey took off for a 72-yard run to the one-yard line. He only saw one target and did not find the end zone, but still had a very productive day and remains a high-end RB1 moving forward.
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